Basically, bad elastin prevents the flex of, well, all body tissues. Tendons and ligaments, muscle sheaths, artery walls, discs. Then, when the elastin breaks down, the byproducts really mess up the calcium system. You end up with calcified all of the above, plus heart valves, aorta, .... It's the root cause of the damaged arteries that the body repairs with a cholesterol patch.
From the abstract:
Many more hits on a search <cardiac elastin calcium>
I've been curious about elastisity since my stiff hands could not do the cub scout salute. Then scoliosis at age 12, hypertension at age 20, diabetes at 25, bad discs at 30yo, heart attack at age 49, stasis dermatitis at 60,and now water on the brain at 67. Calcification everywhere, yet bones with light patches aka 'lucent lesions'. It's a BINGO! for me.
From the abstract:
Quote:
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https://journals.physiology.org/doi/...art.00087.2018 Large, elastic arteries are composed of cells and a specialized extracellular matrix that provides reversible elasticity and strength. Elastin is the matrix protein responsible for this reversible elasticity that reduces the workload on the heart and dampens pulsatile flow in distal arteries. Here, we summarize the elastin protein biochemistry, self-association behavior, cross-linking process, and multistep elastic fiber assembly....... We summarize acquired diseases associated with elastic fiber defects, including hypertension and arterial stiffness, diabetes, obesity, atherosclerosis, calcification, and aneurysms and dissections. .... |
I've been curious about elastisity since my stiff hands could not do the cub scout salute. Then scoliosis at age 12, hypertension at age 20, diabetes at 25, bad discs at 30yo, heart attack at age 49, stasis dermatitis at 60,and now water on the brain at 67. Calcification everywhere, yet bones with light patches aka 'lucent lesions'. It's a BINGO! for me.
via International Skeptics Forum https://ift.tt/38KHRiB
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